Marburg Virus Reservoir

The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 19982000. We found MARV nucleic acid in 12 bats com-prising 3036 of 2 species of insectivorous bat and 1.

Hidden Reservoirs Nature

However the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear.

Marburg virus reservoir. The natural reservoir of the Marburg virus is the African fruit bat. The natural reservoir or host of the Marburg virus is the African fruit bat. Collectively called marburgviruses and have been linked to human cases of Marburg virus disease MVD.

Scientists say once the animal reservoir of the Marburg virus is discovered there would be a better chance of stopping the virus transmission and developing vaccines and treatments. To determine reservoir hosts for Marburg virus MARV we examined the fauna of a mine in northeastern Demo-cratic Republic of the Congo. And in Belgrade Serbia.

Marburg virus disease was initially detected in 1967 after simultaneous outbreaks in Marburg and Frankfurt in Germany. We investigated the clinical and pathologic. Fruit bats infected with Marburg virus do not to show obvious signs of illness.

The reservoir host of Marburg virus is the African fruit bat Rousettus aegyptiacus. Scientists have shown that the Egyptian rousette bat Rousettus aegyptiacus is the natural reservoir for Marburg virus which means the bats can carry the. Egyptian rousette bats Rousettus aegyptiacus are natural reservoir hosts of Marburg virus MARV and Ravn virus RAVV.

The African fruit bat is the reservoir host of the virus. Marburg virus MARV is among the most virulent pathogens of primates including humans. Marburg virus is the causative agent of Marburg virus disease MVD a disease with a case fatality ratio of up to 88 but can be much lower with good patient care.

Although humans have on occasion acquired infection from contact with tissues of diseased nonhuman primates and other mammals the reservoir hosts of the viruses in nature remain unknown. Collectively called marburgviruses and have been linked to human cases of Marburg virus disease MVD. The cave-dwelling mammals carry the virus but do not fall sick from it and can hand the virus to primates in close proximity including humans -- one suspected pathway is the killing or butchering of infected bats for food.

It is generally accepted that Marburg virus is a zoonotic animal borne virus. Previous studies detected antibodies against Marburg virus in the serum of only one of ten species caught. 1 2 MARV a member of the family Filoviridae that includes Ebola virus EBOV is the only human-pathogenic filovirus for which a natural reservoir has been identified.

Fruit bats Rousettus aegyptii are considered the natural host of the virus. Egyptian rousette bats Rousettus aegyptiacus are natural reservoir hosts of Marburg virus MARV and Ravn virus RAVV. It is the Egyptian flying fox Roussettus aegyptiacus a migratory frugivorous bat whose range includes the whole of the African continent south of the tropic of cancer.

The virus takes its name from the German city of Marburg where it was first identified in 1967. Experts from CDC NICD and WHO enter a lead and gold mine in Kitaka about 300 km from Ugandas capital Kampala. The outbreak was associated with a laboratory where workers had been in contact with African green monkeys imported from Uganda.

Monkeys are susceptible to Marburg virus infection but are not considered the reservoir hosts as they die rapidly once infected. In computerized models of prior outbreaks in areas with known zoonotic viral reservoirs in Africa it is estimated that 22 million people are at risk from Ebolavirus infection and 105 million are potentially endangered by Marburg virus infection 45. The Egyptian rousette bat ERB is a natural reservoir host for Marburg virus MARV.

Marburg virus MARV and Ebola virus members of the family Filoviridae cause outbreaks of severe hemorrhagic fever in Africa. Contributors to severe MARV disease include immune response suppression and inflammatory gene dysregulation cytokine storm leading to systemic damage and often death. Primates including humans can become infected with Marburg virus and may develop serious disease with high mortality.

Recorded cases of MVD are rare. Egyptian rousette bats ERBs Rousettus aegyptiacus cave-dwelling fruit bats common across sub-Saharan Africa and parts of the Middle East have been identified as the Marburg virus MARV natural reservoir. Scientists in the West African nation of Sierra Leone found live bats infected with Marburg in 2018 but no cases were confirmed in humans.

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