Marburg Virus Characteristics

Marburg virus Filoviridae causes severe hemorrhagic fevers in humans and some lower primates with high mortality. Marburg disease Marburg haemorrhagic fever African haemorrhagic fever and green monkey disease12.

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Symptoms of Marburg virus disease The incubation period varies from 2 to 21 days.

Marburg virus characteristics. The initial symptoms of the virus include high fever severe headache and severe malaise. Publisher Name Springer Berlin Heidelberg. Marburg virus SYNONYM OR CROSS REFERENCE.

1971 Some Characteristics of the Marburg Virus. Marburg virus disease is transmitted to people from fruit bats and spreads between humans through the transmission of bodily fluids. Eds Marburg Virus Disease.

Marburg hemorrhagic fever Marburg HF is a rare but severe hemorrhagic fever which affects both humans and non-human primates. Although the main route of infection is known to be person-to-person transmission by intimate contact the natural reservoir for filoviruses still remains a mystery. Fruit bats infected with Marburg virus do not to show obvious signs of illness.

The five species of Ebola virus are the only other known members of the filovirus family. In humans marburgviruses are responsible for Marburg virus disease MVD a zoonotic disease that is characterized by high fever malaise nausea vomiting diarrhea skin rash and hemorrhage bleeding. Ebola and Marburg viruses MARV are members of the Filoviridae and induce a serious hemorrhagic disease.

Further study is needed to determine if other species may also host the virus. Martini GA Siegert R. Marburg virus is a member of the Filoviridae family and is an elongated filamentous molecule highly variable in length but typically around 1000 nm long with a uniform diameter of 80 nm23.

Marburg virus MARV is a lipid-enveloped virus harboring a negative sense RNA genome which has caused sporadic outbreaks of viral hemorrhagic fever in Sub-Saharan Africa. The filoviruses most commonly associated with causing human disease are MARV and Ebola virus formerly known as Ebola Zaire EBOV. Ebola and Marburg viruses make up a family of negative single-stranded ss RNA viruses known as the Filoviruses which form long thin filaments Fig.

Marburg HF is caused by Marburg virus a genetically unique zoonotic or animal-borne RNA virus of the filovirus family. The case fatality rates CFR reported in the various outbreaks range from 24 to 100. Primates including humans can become infected with Marburg virus and may develop serious disease with high mortality.

Kunz C Hofmann H. Marburg virus was first isolated during an outbreak in Europe in 1967 and Ebola virus emerged in 1976 as the causative agent of two simultaneous outbreaks in southern Sudan and northern Zaire. MVD case fatality rates have been as high as 80 to 90 percent.

The virus genome is formed by a single strand RNA of negative polarity coding for seven structural proteins. Patients vomit and ooze blood from various orifices including their eyes and ears. Continue reading more about Marburg.

Cases are extremely rare with the last major outbreak in.

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