Marburg Virus Epidemiology

Marburg Virus Disease MVD is a severe infectious disease caused by Marburg virus a member of the Filoviridae family which also includes Ebola viruses. 18 caused by the Ebola virus and eight by the Marburg virus.

Marburgvirus An Overview Sciencedirect Topics

It is generally accepted that Marburg virus is a zoonotic animal borne virus.

Marburg virus epidemiology. Marburg virus disease MVD formerly known as Marburg haemorrhagic fever is a severe often fatal illness in humans. In order to provide health-care workers in risk areas with a working tool to. Ebola or Marburg haemorrhagic fever outbreaks constitute a major public health issue in Sub-Saharan Africa.

The Marburg virus is transmitted to people from fruit bats and spreads among humans. This outbreak was a result of the inadvertent importation of infected vervet monkeys Chlorocebus pygerythrus from Uganda for use in vaccine production. Rousettus aegyptiacus fruit bats of the Pteropodidae family are considered to be natural hosts of Marburg virus.

The Marburg virus was the first filovirus to be discovered after simultaneous outbreaks in several European laboratories including one in Marburg Germany in 1967. Martini GA Siegert R. The initial transmission to humans on this occasion was likely due to contact with infected African green monkeys.

About 2551 cases have been reported among which 268 were health workers 93. The overall fatality rate was 23 percent. Marburg virus was first recognized in 1967 when outbreaks of haemorrhagic fever occurred in laboratories located in Marburg and Frankfurt Germany and Belgrade Yugoslavia present-day Serbia.

Endemic areas The first recognized outbreak of Marburg virus disease occurred in Germany and Yugoslavia in 1967. 13 rows World Health Organization. Epidemiology of marburg hemorrhagic fever 1.

Epidemic outbreaks of Marburg and Ebola viruses have taken a heavy toll on human life in Central Africa and devastated large ape populations in Gabon and Republic of Congo. Epidemics have occurred sporadically since the discovery of Marburg in 1967 and Ebola virus in 1976. Marburg virus was first recognized in 1967 when outbreaks of hemorrhagic fever occurred simultaneously in laboratories in Marburg and Frankfurt Germany and in Belgrade Yugoslavia now Serbia.

Since their discovery in 1967 Marburg and 1976 Ebola more than 2300 cases and 1670 deaths have been reported. Recorded cases of MVD are rare. Publisher Name Springer Berlin Heidelberg.

Of the 2 870 Marburg and Ebola cases documented between June 1967 and June 2011 270 9 were health-care workers. Fruit bats Rousettus aegyptii are considered the natural host of the virus. While some of these outbreaks have been relatively large infecting a few hundreds of individuals they have generally occurred in rural settings and have been controlled relatively easily.

Monkeys are susceptible to Marburg virus infection but are not considered the reservoir hosts as they die rapidly once infected. MHF was first described in 1967 during outbreaks in Germany and the former Yugoslavia that were linked to monkeys imported from Uganda 1 3. Eds Marburg Virus Disease.

Biotechnology RIDDHI KARNIK Topic -Epidemiology of Marburg virus Hemorrhagic Fever Outbreaks Marburg virus MARV forms its own genus within the family Filoviridae and at present only a single species Lake Victoria Marburg virus has been described. Marburg hemorrhagic fever MHF is a severe illness caused by Marburg virus a member of the Filoviridae family. 1971 Epidemiology of Marburg Virus Disease.

Overall 26 hemorrhagic epidemic outbreaks have been registered in 12 countries. Thirty-one people became ill initially laboratory workers followed by several medical personnel and family members who had cared for them. Assignment BT-208 Exercises in Virology Roll no- 11333 MSc.

Marburg virus disease - South Africa.

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